INT166811

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.18
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Casq1) Golgi apparatus (Casq1) molecular_function (Casq1)
response to stress (Casq1) cytoplasm (Casq1)
Casq1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 2 96.44 Very High Very High Very High
Inflammation 32 50.00 Quite Low
Acupuncture 12 5.00 Very Low Very Low Very Low
imagery 7 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
bradykinin 4 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Myofascial pain syndrome 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 52 98.72 Very High Very High Very High
Muscle Disease 5 98.24 Very High Very High Very High
Myalgia 3 96.72 Very High Very High Very High
Muscle Weakness 1 95.44 Very High Very High Very High
Graves' Ophthalmopathy 60 88.68 High High
Thyroid Disease 18 82.12 Quite High
INFLAMMATION 35 50.00 Quite Low
Myocardial Infarction 4 47.12 Quite Low
Apoptosis 25 42.40 Quite Low
Lymphatic System Cancer 1 30.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There were no significant changes in L-type Ca2+ channel and calsequestrin mRNA transcription levels when hypoxia-reoxygenated cells were treated with thiopental.
Neg (no) Regulation (changes) of calsequestrin associated with hypoxia
1) Confidence 0.04 Published 2010 Journal Yonsei Medical Journal Section Body Doc Link PMC2824862 Disease Relevance 0.57 Pain Relevance 0
Calsequestrin and junctin immunoreactivity in hexagonally cross-linked tubular arrays myopathy.
Regulation (immunoreactivity) of Calsequestrin associated with muscle disease
2) Confidence 0.03 Published 2010 Journal Neuromuscul. Disord. Section Title Doc Link 20211563 Disease Relevance 0.37 Pain Relevance 0.10
In relation to eccentric changes due to chronic cardiac volume overload, changes in Ca2+ and calsequestrin can result in altered contraction responsiveness to Ca2+ [134].
Regulation (changes) of calsequestrin
3) Confidence 0.00 Published 2007 Journal BMC Musculoskelet Disord Section Body Doc Link PMC1820789 Disease Relevance 0.24 Pain Relevance 0

General Comments

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