INT166839

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.88
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein binding, bridging (ANXA1) cilium (ANXA1) protein complex (ANXA1)
lipid metabolic process (ANXA1) cytoplasm (ANXA1) signal transduction (ANXA1)
ANXA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 4 95.80 Very High Very High Very High
dexamethasone 1 89.04 High High
Potency 1 77.64 Quite High
cINOD 2 75.00 Quite High
aspirin 4 66.52 Quite High
Disease Link Frequency Relevance Heat
Cancer 3 99.08 Very High Very High Very High
Colon Cancer 1 96.88 Very High Very High Very High
INFLAMMATION 6 95.80 Very High Very High Very High
Apoptosis 1 81.28 Quite High
Pancreatic Cancer 1 68.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our findings reveal that ANXA1 is an inducible endogenous inhibitor of NF-kappaB in human cancer cells and mice, provide a novel molecular mechanism for the action of anti-inflammatory agents, and suggest the possibility of mechanism-driven drug development.
Negative_regulation (inhibitor) of ANXA1 associated with inflammation and cancer
1) Confidence 0.37 Published 2010 Journal Cancer Res. Section Abstract Doc Link 20215502 Disease Relevance 0.88 Pain Relevance 0.43

General Comments

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