INT166880

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Context Info
Confidence 0.57
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 1.01

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ccl3) extracellular space (Ccl3) extracellular region (Ccl3)
intracellular (Ccl3) cytoskeleton organization (Ccl3) kinase activity (Ccl3)
Anatomy Link Frequency
macrophage 2
Ccl3 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuropathic pain 5 99.90 Very High Very High Very High
Nicotine 1 98.42 Very High Very High Very High
Sciatic nerve 5 87.04 High High
Thermal hyperalgesia 3 79.92 Quite High
Inflammation 5 75.00 Quite High
Peripheral nerve injury 1 75.00 Quite High
Brush evoked pain 3 74.60 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 8 99.90 Very High Very High Very High
Hyperalgesia 3 79.92 Quite High
INFLAMMATION 2 75.00 Quite High
Nervous System Injury 1 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Perineural injection of nicotine (20nmol), a macrophage suppressor, prevented PSL-induced neuropathic pain and suppressed MIP-1alpha and IL-1beta expressions.
Negative_regulation (suppressed) of Gene_expression (expressions) of MIP-1alpha in macrophage associated with nicotine and neuropathic pain
1) Confidence 0.57 Published 2010 Journal Pain Section Abstract Doc Link 20223588 Disease Relevance 0.81 Pain Relevance 1.01

General Comments

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