INT166936

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Context Info
Confidence 0.43
First Reported 2009
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.22
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR1I2) signal transduction (NR1I2) nucleus (NR1I2)
Anatomy Link Frequency
liver 2
obturator nerve 2
NR1I2 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 1 99.98 Very High Very High Very High
nerve block 1 99.80 Very High Very High Very High
anesthesia 1 75.00 Quite High
agonist 13 52.48 Quite High
Bile 9 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemorrhage 1 85.48 High High
Bladder Cancer 2 75.00 Quite High
Obesity 1 38.08 Quite Low
Van Bogaert's Disease 7 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Gallstones 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Syndrome 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We consider that evaluation of the necessary precautions, such as the obturator nerve block, for the prevention of the ONR is important even in the surgery using the TURis system.
Positive_regulation (important) of Neg (prevention) Gene_expression (prevention) of ONR in obturator nerve associated with nerve block
1) Confidence 0.43 Published 2010 Journal Masui Section Abstract Doc Link 20229762 Disease Relevance 0.22 Pain Relevance 0.17
GR-activating concentrations of glucocorticoid transactivated SULT2A transcription indirectly, through intermediary steps involving GR-inducible liver-enriched CCAAT enhancer binding protein [128], while pharmacological concentrations of dexamethasone induced rat hepatic SULT2A expression via a PXR-mediated mechanism [127].
Positive_regulation (induced) of Gene_expression (expression) of PXR in liver associated with dexamethasone
2) Confidence 0.18 Published 2009 Journal PPAR Research Section Body Doc Link PMC2724710 Disease Relevance 0 Pain Relevance 0.08

General Comments

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