INT166947

Context Info Confidence 0.00 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.47 Pain Relevance 1.86

extracellular space (Ngf, KNG1) extracellular region (Ngf, KNG1) signal transduction (Ngf) plasma membrane (KNG1)

Anatomy Link Frequency nerve 1 Ngf (Mus musculus) KNG1 (Homo sapiens)

Pain Link Frequency Relevance Heat Inflammation 5 100.00 Nerve growth factor 1 100.00 adenocard 1 100.00 bradykinin 1 100.00 analgesia 3 97.20 Neuropeptide 1 95.84 nociceptor 3 94.80 qutenza 4 89.60 burning pain 1 84.68 Analgesic 6 77.92

Disease Link Frequency Relevance Heat INFLAMMATION 3 100.00 Pain 3 84.68 Intractable Pain 1 64.56 Injury 1 46.48

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Moreover, the realization that TRPV1 is both sensitized and activated by endogenous products of inflammation, including bradykinin, H+, adenosine triphosphate, fatty acid derivatives, nerve growth factor, and trypsins, has renewed interest in TRPV1 as an important site of analgesia.

nerve growth factor Positive_regulation (activated) of bradykinin in nerve associated with adenocard, nerve growth factor, inflammation, bradykinin and analgesia

1) Confidence 0.00 Published 2010 Journal Pain Pract Section Abstract Doc Link 20230457 Disease Relevance 0.47 Pain Relevance 1.86

General Comments

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