INT167019

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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.76
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Ldlr) transport (Ldlr) aging (Ldlr)
plasma membrane (Ldlr) lipid metabolic process (Ldlr) lysosome (Ldlr)
Anatomy Link Frequency
liver 2
Ldlr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Restless leg syndrome 2 82.96 Quite High
Inflammation 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 9 100.00 Very High Very High Very High
Hyperlipidemia 13 98.80 Very High Very High Very High
Disease 9 87.92 High High
Thrombosis 1 86.96 High High
Increased Venous Pressure Under Development 4 82.96 Quite High
Cardiovascular Disease 35 73.56 Quite High
Coronary Artery Disease 4 53.52 Quite High
Nicotine Addiction 5 29.52 Quite Low
Obesity 5 5.00 Very Low Very Low Very Low
Chronic Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cuban studies claim that 1 to 20 mg/day of the original PC supplement are effective at producing significant reductions in total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C).
Negative_regulation (reductions) of Gene_expression (producing) of low density lipoprotein cholesterol associated with disorder of lipid metabolism
1) Confidence 0.42 Published 2010 Journal Crit Rev Food Sci Nutr Section Abstract Doc Link 20301014 Disease Relevance 0.27 Pain Relevance 0.08
The plant stanol ester margarine BenecolĀ® (Raisio Group, Raisio, Finland), launched in Finland in 1995, is an example of a functional food that has been shown to lower effectively serum total and LDL-cholesterol levels in several interventions [5,6].
Negative_regulation (lower) of Gene_expression (levels) of LDL-cholesterol
2) Confidence 0.32 Published 2005 Journal Nutr J Section Body Doc Link PMC1177987 Disease Relevance 0.22 Pain Relevance 0
In contrast, the serum LDL-cholesterol levels and liver xanthine oxidase (XO) activity in WJ diet groups were significantly decreased.
Negative_regulation (decreased) of Gene_expression (levels) of LDL-cholesterol in liver
3) Confidence 0.01 Published 2010 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Abstract Doc Link PMC2892354 Disease Relevance 0.27 Pain Relevance 0

General Comments

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