INT167050

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 2.28

Gt(pU21)50Imeg (Mus musculus)

Pain Link Frequency Relevance Heat Antinociceptive 5 99.98 Oxycodone 8 99.64 narcan 1 99.26 antagonist 4 99.08 Opioid 1 98.86 antinociception 8 98.44 tolerance 5 91.80 opioid receptor 3 80.40 agonist 5 79.12 Kappa opioid receptor 3 75.00

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Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Opioid-antagonist naloxone, completely blocked antinociceptive effect of DAMGO, SNC80, U50,488H or oxycodone and potentiation of antinociception by BMS182874.

Negative_regulation (effect) of U50 associated with antinociception, oxycodone, antagonist, narcan, antinociceptive and opioid

1) Confidence 0.01 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20303944 Disease Relevance 0 Pain Relevance 2.28

General Comments

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