INT167064

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.50
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Nr3c2) nucleus (Nr3c2) cytoplasm (Nr3c2)
Nr3c2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 1 96.20 Very High Very High Very High
fibrosis 1 94.52 High High
antidepressant 1 90.60 High High
corticosteroid 8 86.32 High High
Calcium channel 7 84.80 Quite High
Angina 1 80.48 Quite High
antagonist 3 75.00 Quite High
Hippocampus 29 65.04 Quite High
depression 2 51.32 Quite High
dexamethasone 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 10 98.04 Very High Very High Very High
Vasculitis 1 96.56 Very High Very High Very High
Fibrosis 1 94.52 High High
Stress 54 93.32 High High
Hypertension 2 81.84 Quite High
Cv General 3 Under Development 1 80.48 Quite High
Post-traumatic Stress Disorder 27 66.64 Quite High
Apoptosis 2 62.64 Quite High
Neurodegenerative Disease 2 56.96 Quite High
Depression 2 51.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aldosterone-induced activation of mineralocorticoid receptor, a member of the nuclear receptor family, results in increased tissue damage such as vascular inflammation and cardiac and perivascular fibrosis.
Positive_regulation (induced) of Positive_regulation (activation) of mineralocorticoid receptor associated with fibrosis, inflammation and vasculitis
1) Confidence 0.44 Published 2010 Journal Eur. J. Pharmacol. Section Abstract Doc Link 20307534 Disease Relevance 0.35 Pain Relevance 0.35
These studies examined whether changes in hippocampal MR and GR could mediate both behavioral/emotional changes in psychiatric disorders.
Positive_regulation (mediate) of Positive_regulation (hippocampal) of MR
2) Confidence 0.42 Published 2008 Journal Acta Histochemica et Cytochemica Section Body Doc Link PMC2532603 Disease Relevance 1.14 Pain Relevance 0.21

General Comments

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