INT167278

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.94
Pain Relevance 1.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (OPRM1) endoplasmic reticulum (OPRM1) intracellular (REST)
DNA binding (REST) cytoplasm (REST) signal transducer activity (OPRM1)
Anatomy Link Frequency
nerve 1
OPRM1 (Homo sapiens)
REST (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 4 100.00 Very High Very High Very High
dorsal root ganglion 3 94.52 High High
sodium channel 1 86.96 High High
c fibre 4 85.28 High High
Hypoesthesia 2 84.64 Quite High
Morphine 1 81.20 Quite High
analgesia 1 80.48 Quite High
Neuropathic pain 3 75.00 Quite High
Peripheral nerve injury 1 71.96 Quite High
Pain 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Nervous System Injury 4 99.80 Very High Very High Very High
Ganglion Cysts 3 94.52 High High
Hypesthesia 2 84.64 Quite High
Neuropathic Pain 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, chromatin immunoprecipitation analysis revealed that nerve injury promotes NRSF binding to the neuron-restrictive silencer element within MOP and Na(v)1.8 genes, thereby causing epigenetic silencing.
MOP Binding (binding) of NRSF in nerve associated with nervous system injury and opioid receptor
1) Confidence 0.08 Published 2010 Journal J. Neurosci. Section Abstract Doc Link 20357131 Disease Relevance 0.94 Pain Relevance 1.24

General Comments

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