INT167375

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Context Info
Confidence 0.73
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.62
Pain Relevance 0.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (Acta2) cytoplasm (Acta2)
Anatomy Link Frequency
smooth muscle 2
PSC 1
F4/80 1
Acta2 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 10 96.80 Very High Very High Very High
alcohol 2 90.72 High High
Chronic pancreatitis 8 81.04 Quite High
Inflammation 1 69.32 Quite High
anesthesia 7 58.16 Quite High
isoflurane 2 57.72 Quite High
dexamethasone 4 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Paracetamol 2 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 5 99.16 Very High Very High Very High
Fibrosis 10 96.80 Very High Very High Very High
Pancreatitis 9 89.92 High High
Adhesions 1 88.48 High High
Keloid Scars 1 69.88 Quite High
INFLAMMATION 1 69.32 Quite High
Necrosis 3 68.76 Quite High
Disease 3 65.36 Quite High
Cancer 106 59.76 Quite High
Severe Combined Immunodeficiency 10 39.96 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Primary antibodies for ASMA, CD31 and F4/80 were detected using either biotinylated rabbit-anti-mouse antibodies (1:500, E0354, DAKO) visualized by Vectastain ABC-HRP kit (1:100, Vector Laboratories), or biotinylated rabbit-anti-goat antibodies (1:500, E0466, DAKO) visualized by Vectastain ABC-AP kit (1:100, Vector Laboratories), or biotinylated goat-anti-rat antibodies (10 ?
Localization (biotinylated) of ASMA in F4/80
1) Confidence 0.73 Published 2007 Journal BMC Cancer Section Body Doc Link PMC2234427 Disease Relevance 0.15 Pain Relevance 0.09
In mice receiving ethanol plus cerulein, there was increased collagen deposition as compared with other treatment groups as well as increased frequency of alpha-smooth muscle actin and desmin-positive PSC, which also showed significantly enhanced CTGF protein production.
Localization (frequency) of alpha-smooth muscle actin in PSC associated with primary sclerosing cholangitis
2) Confidence 0.31 Published 2010 Journal Lab. Invest. Section Abstract Doc Link 20368699 Disease Relevance 1.28 Pain Relevance 0.68
Engrafted MSC in liver express alpha smooth muscle actin and their localization merges with collagen deposition
Localization (localization) of alpha smooth muscle actin in smooth muscle
3) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.10 Pain Relevance 0.05
Engrafted MSC in liver express alpha smooth muscle actin and their localization merges with collagen deposition
Localization (liver) of alpha smooth muscle actin in smooth muscle
4) Confidence 0.05 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722022 Disease Relevance 0.09 Pain Relevance 0.05

General Comments

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