INT167377

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.35
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ctgf) cytosol (Ctgf) extracellular space (Ctgf)
extracellular region (Ctgf) Golgi apparatus (Ctgf) proteinaceous extracellular matrix (Ctgf)
Anatomy Link Frequency
connective tissue 2
Ctgf (Mus musculus)
Pain Link Frequency Relevance Heat
alcohol 2 99.30 Very High Very High Very High
Chronic pancreatitis 8 97.76 Very High Very High Very High
Inflammation 8 88.52 High High
cytokine 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fibrosis 4 99.64 Very High Very High Very High
Pancreatitis 9 97.76 Very High Very High Very High
Primary Sclerosing Cholangitis 5 93.28 High High
Keloid Scars 1 89.08 High High
Atherosclerosis 35 88.88 High High
INFLAMMATION 8 88.52 High High
Necrosis 1 87.96 High High
Disorder Of Lipid Metabolism 3 87.04 High High
Atherosclerotic Plaque 3 39.76 Quite Low
Disease 2 29.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The aim of this study was to establish a model of ACP in mice, a species that is usually resistant to the toxic effects of alcohol, and to identify the cell type(s) responsible for production of connective tissue growth factor (CTGF), a pro-fibrotic molecule.
Regulation (responsible) of Gene_expression (production) of CTGF in connective tissue associated with fibrosis, chronic pancreatitis and alcohol
1) Confidence 0.25 Published 2010 Journal Lab. Invest. Section Abstract Doc Link 20368699 Disease Relevance 0.95 Pain Relevance 0.48
by statins regulates CTGF overproduction.


Regulation (regulates) of Gene_expression (overproduction) of CTGF
2) Confidence 0.19 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2597201 Disease Relevance 0.39 Pain Relevance 0

General Comments

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