INT167392

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Context Info
Confidence 0.21
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.93
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Gins4) cytoplasm (Gins4)
Anatomy Link Frequency
medial 1
Gins4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 17 98.96 Very High Very High Very High
GABAergic 1 96.24 Very High Very High Very High
Locus ceruleus 16 82.24 Quite High
Glutamate 1 57.52 Quite High
agonist 2 56.72 Quite High
cINOD 1 44.80 Quite Low
parabrachial 4 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Central grey 2 5.00 Very Low Very Low Very Low
cerebral cortex 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 1 99.12 Very High Very High Very High
Stress 5 94.80 High High
Injury 6 78.56 Quite High
Necrosis 1 55.04 Quite High
Cancer 1 54.68 Quite High
Hepatotoxicity 2 51.72 Quite High
INFLAMMATION 1 44.56 Quite Low
Muscle Hypertonia 14 11.12 Low Low
Body Weight 5 5.00 Very Low Very Low Very Low
Sleep Disorders 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Either antioxidant tempol or a pancaspase inhibitor Z-VAD-FMK decreased cell death as well as caspase 3/7 activity induced by SLD sulfide/TNF coexposure.
Gene_expression (coexposure) of SLD associated with death
1) Confidence 0.21 Published 2010 Journal Toxicology Section Abstract Doc Link 20371263 Disease Relevance 0.93 Pain Relevance 0
Moreover, it was demonstrated that the SLD projects to neurons in the medial medulla that also stain positively for glycine [44].
Gene_expression (projects) of SLD in medial associated with medulla
2) Confidence 0.03 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1079781 Disease Relevance 0 Pain Relevance 0.36

General Comments

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