INT167456

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Context Info
Confidence 0.14
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.76
Pain Relevance 1.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nr3c1) nucleus (Nr3c1) intracellular (Nr3c1)
DNA binding (Nr3c1) protein complex (Nr3c1) transcription factor binding (Nr3c1)
Anatomy Link Frequency
pituitary 2
Nr3c1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 172 100.00 Very High Very High Very High
fluoxetine 5 100.00 Very High Very High Very High
tricyclic antidepressant 5 99.60 Very High Very High Very High
depression 6 96.84 Very High Very High Very High
Physical dependence 10 92.64 High High
monoamine 1 86.44 High High
antidepressant 1 78.52 Quite High
antagonist 6 77.76 Quite High
sSRI 4 75.56 Quite High
amygdala 3 51.24 Quite High
Disease Link Frequency Relevance Heat
Depression 8 97.32 Very High Very High Very High
Drug Dependence 12 92.64 High High
Sprains And Strains 82 88.64 High High
Adhesions 1 32.20 Quite Low
Skin Cancer 1 31.64 Quite Low
Nervous System Malformation 4 22.68 Low Low
Shock 8 5.00 Very Low Very Low Very Low
Opiate Addiction 8 5.00 Very Low Very Low Very Low
Apoptosis 8 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Widespread hypothalamic-pituitary-adrenocortical axis-relevant and mood-relevant effects of chronic fluoxetine treatment on glucocorticoid receptor gene expression in mice.
Regulation (effects) of Gene_expression (expression) of glucocorticoid receptor in pituitary associated with fluoxetine
1) Confidence 0.14 Published 2010 Journal Eur. J. Neurosci. Section Title Doc Link 20374287 Disease Relevance 0.58 Pain Relevance 0.82
Modulation of behavioral effects of morphine by glucocorticoid receptor blockade
Regulation (Modulation) of Gene_expression (blockade) of glucocorticoid receptor associated with morphine
2) Confidence 0.14 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394777 Disease Relevance 0.18 Pain Relevance 1.05

General Comments

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