INT167529

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Context Info
Confidence 0.26
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 1.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ppt1, Trpv1) cofactor metabolic process (Ppt1) Golgi apparatus (Ppt1)
lipid metabolic process (Trpv1) extracellular space (Ppt1) protein modification process (Ppt1)
Ppt1 (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
qutenza 12 99.84 Very High Very High Very High
dorsal root ganglion 5 95.36 Very High Very High Very High
substance P 7 94.12 High High
Root ganglion neuron 1 75.00 Quite High
Pain 1 56.24 Quite High
Inflammation 1 54.72 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 6 95.36 Very High Very High Very High
Pain 1 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Preprotachykinin (PPT) mRNA, TRPV1 mRNA and TRPV1 protein expression decreased in CAP-treated cultures and RTX cultures treated with the higher concentration, whereas RTX cultures treated with the lower concentration were not affected.
PPT Negative_regulation (decreased) of Gene_expression (expression) of TRPV1 protein associated with qutenza
1) Confidence 0.26 Published 2010 Journal Methods Find Exp Clin Pharmacol Section Abstract Doc Link 20383340 Disease Relevance 0.49 Pain Relevance 1.38

General Comments

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