INT167536

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Context Info
Confidence 0.49
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (BRCA2) chromosome organization (BRCA2) nucleolus (BRCA2)
nucleus (BRCA2) cell cycle (BRCA2) DNA binding (BRCA2)
BRCA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 3 25.00 Low Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 4 75.00 Quite High
Nerve Degeneration 1 50.96 Quite High
Renal Failure 1 50.04 Quite High
Blindness 1 49.40 Quite Low
Stroke 1 48.44 Quite Low
Disease 1 48.12 Quite Low
Hyperglycemia 1 46.48 Quite Low
Pain 3 25.00 Low Low
Obesity 1 25.00 Low Low
Cancer 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Initially the system used pyrroloquinoline quinone (PQQ)-dependent GDH but now uses flavin adenine dinucleotide (FAD)-dependent GDH.
Positive_regulation (dependent) of FAD
1) Confidence 0.49 Published 2010 Journal Acc. Chem. Res. Section Abstract Doc Link 20384299 Disease Relevance 0.29 Pain Relevance 0
RAD51 paralogs and BRCA2) are required for RAD51 foci formation (46,47).
Positive_regulation (required) of BRCA2
2) Confidence 0.05 Published 2009 Journal Nucleic Acids Research Section Body Doc Link PMC2770670 Disease Relevance 0 Pain Relevance 0

General Comments

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