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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.36

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intracellular (Sp1) DNA binding (Sp1) signal transducer activity (Oprm1)
cytoplasm (Sp1) signal transduction (Oprm1) nucleolus (Sp1)
Sp1 (Rattus norvegicus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
mu opioid receptor 8 100.00 Very High Very High Very High
opioid receptor 1 75.00 Quite High
Morphine 1 64.48 Quite High
Disease Link Frequency Relevance Heat
Embryonal Carcinoma 1 70.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overexpression of Sp1 strongly enhanced MOR promoter activity, and the histone deacetylase inhibitor trichostatin A also increased promoter activity.
Gene_expression (Overexpression) of Sp1 Positive_regulation (enhanced) of MOR promoter associated with mu opioid receptor
1) Confidence 0.03 Published 2010 Journal Mol. Pharmacol. Section Abstract Doc Link 20385708 Disease Relevance 0.07 Pain Relevance 0.36

General Comments

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