INT167582

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (ENPP2, LPA) transport (LPA) small molecule metabolic process (LPA)
lipid metabolic process (LPA) extracellular space (ENPP2) peptidase activity (LPA)
ENPP2 (Homo sapiens)
LPA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 8 97.20 Very High Very High Very High
Arthritis 1 94.72 High High
Multiple sclerosis 1 94.12 High High
cytokine 1 81.20 Quite High
Bioavailability 1 44.96 Quite Low
Hyperalgesia 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 8 97.20 Very High Very High Very High
Cancer 1 95.04 Very High Very High Very High
Arthritis 1 94.72 High High
Demyelinating Disease 1 94.12 High High
Disease 1 73.36 Quite High
Hyperalgesia 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Autotaxin is the enzyme responsible for the production of lysophosphatidic acid (LPA) from lysophosphatidyl choline (LPC), and it is up-regulated in many inflammatory conditions, including but not limited to cancer, arthritis, and multiple sclerosis.
Autotaxin Regulation (responsible) of Gene_expression (production) of LPA associated with multiple sclerosis, inflammation, cancer and arthritis
1) Confidence 0.05 Published 2010 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 20392816 Disease Relevance 0.61 Pain Relevance 0.26

General Comments

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