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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.47
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Rock2) cytoskeleton (Rock2) nucleus (Rock2)
kinase activity (Rock2) microtubule organizing center (Rock2) cytoplasm (Rock2)
Anatomy Link Frequency
neurons 1
bladder 1
Rock2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Abeta 10 86.04 High High
depression 1 80.36 Quite High
interstitial cystitis 4 67.12 Quite High
cINOD 1 61.84 Quite High
Pain 2 47.88 Quite Low
Dopamine 6 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
pain pelvic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 84 98.84 Very High Very High Very High
Drug Induced Neurotoxicity 3 98.76 Very High Very High Very High
Overactive Bladder 28 96.00 Very High Very High Very High
Neurodegenerative Disease 1 94.72 High High
Disease 8 92.72 High High
Amyloid Plaque 1 88.84 High High
Alzheimer's Dementia 4 86.60 High High
Depression 1 80.36 Quite High
Anxiety Disorder 1 79.72 Quite High
Conversion Disorder 1 79.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The protective effect of Rho-associated kinase inhibitor on aluminum-induced neurotoxicity in rat cortical neurons.
Regulation (effect) of Rho-associated kinase in neurons associated with drug induced neurotoxicity
1) Confidence 0.33 Published 2010 Journal Toxicol. Sci. Section Title Doc Link 20395307 Disease Relevance 0.86 Pain Relevance 0.42
This study examined the effect of stress on the pathophysiology of bladder stability by observing changes in enzymes, Rho-kinase, and two types of collagen, which are required for proper muscle activity and stability within the bladder.
Regulation (changes) of Rho-kinase in bladder associated with stress
2) Confidence 0.26 Published 2010 Journal Korean Journal of Urology Section Body Doc Link PMC2855479 Disease Relevance 1.61 Pain Relevance 0.17

General Comments

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