INT167647

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Context Info
Confidence 0.32
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 3.21
Pain Relevance 3.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
spinal 1
plasma 1
leg 1
PTPN5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 693 100.00 Very High Very High Very High
backache 342 99.80 Very High Very High Very High
Neuropathic pain 144 98.92 Very High Very High Very High
imagery 81 98.38 Very High Very High Very High
tramadol 1 93.12 High High
Analgesic 24 69.36 Quite High
Brush evoked pain 6 62.88 Quite High
burning pain 9 61.36 Quite High
Hyperalgesia 21 60.72 Quite High
allodynia 9 50.08 Quite High
Disease Link Frequency Relevance Heat
Pain 693 100.00 Very High Very High Very High
Low Back Pain 354 99.80 Very High Very High Very High
Neuropathic Pain 234 98.92 Very High Very High Very High
Cancer 6 70.08 Quite High
Infection 6 69.68 Quite High
Neurologic Manifestations 3 66.20 Quite High
Hyperalgesia 24 60.72 Quite High
Diabetic Neuropathy 45 5.00 Very Low Very Low Very Low
Post Operative Pain 39 5.00 Very Low Very Low Very Low
Disease 39 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One-step protein precipitation with acetonitrile was used to extract the analytes from the plasma.
One-step Binding (precipitation) of in plasma
1) Confidence 0.32 Published 2010 Journal J Pharm Biomed Anal Section Abstract Doc Link 20399588 Disease Relevance 0 Pain Relevance 0.09
However, we believe that the interview questions and physical tests included in StEP will be sufficient, because StEP was still highly sensitive and specific in discriminating between radicular and axial LBP after excluding the straight-leg-raising sign, which has utility only for the diagnosis of radicular LBP.
StEP Binding (sufficient) of in leg associated with pain and backache
2) Confidence 0.21 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2661253 Disease Relevance 1.25 Pain Relevance 1.22
We compared StEP with a screening tool for neuropathic pain, the DN4 [24], which consists of seven interview questions and three physical tests.
StEP Binding (compared) of associated with pain and neuropathic pain
3) Confidence 0.21 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2661253 Disease Relevance 1.15 Pain Relevance 1.22
We found that spinal MRI is a sensitive diagnostic tool for the identification of radicular LBP, but its specificity was lower than that of two clinical methods, StEP and DN4, despite the application of standardized evaluation criteria.
StEP Binding (specificity) of in spinal associated with pain, imagery and backache
4) Confidence 0.20 Published 2009 Journal PLoS Medicine Section Body Doc Link PMC2661253 Disease Relevance 0.81 Pain Relevance 0.85

General Comments

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