INT167649

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Context Info
Confidence 0.07
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.20
Pain Relevance 0.55

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Polr2f) nucleus (Polr2f) DNA binding (Polr2f)
Polr2f (Mus musculus)
Pain Link Frequency Relevance Heat
Nerve growth factor 8 99.08 Very High Very High Very High
imagery 12 83.96 Quite High
opioid receptor 4 75.00 Quite High
Pain 1 60.64 Quite High
isoflurane 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 46 76.48 Quite High
Cytomegalovirus Infection 26 64.36 Quite High
Pain 1 60.64 Quite High
Infection 2 20.40 Low Low
Repression 9 5.00 Very Low Very Low Very Low
Targeted Disruption 5 5.00 Very Low Very Low Very Low
Melanoma 5 5.00 Very Low Very Low Very Low
Brain Tumor 4 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 2 5.00 Very Low Very Low Very Low
Skin Cancer 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We conclude that the retroviral pHUSH vector is capable of inducible pol III-shRNA expression, pol II-miRNA expression, and pol II-protein expression.
Positive_regulation (capable) of pol II
1) Confidence 0.07 Published 2007 Journal BMC Biotechnol Section Body Doc Link PMC2174931 Disease Relevance 0.14 Pain Relevance 0.04
We also found that assembling of RNA polymerase II (Pol II) at the promoter took place before NGF stimulation, indicating that p300 could only interact with preassembled Pol II at the promoter after NGF stimulation.
Positive_regulation (preassembled) of Pol II associated with nerve growth factor
2) Confidence 0.04 Published 2010 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 20399742 Disease Relevance 0.06 Pain Relevance 0.51

General Comments

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