INT167656

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Context Info
Confidence 0.43
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.22
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Hmgb1) cell morphogenesis (Hmgb1) nucleolus (Hmgb1)
chromosome (Hmgb1) nucleus (Hmgb1) transcription factor binding (Hmgb1)
Anatomy Link Frequency
spinal 2
Hmgb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
allodynia 4 99.56 Very High Very High Very High
Cancer pain 4 91.80 High High
spinal dorsal horn 3 88.00 High High
cytokine 1 86.96 High High
Inflammation 1 84.28 Quite High
Pain 4 73.88 Quite High
intrathecal 1 64.00 Quite High
Disease Link Frequency Relevance Heat
Neuropathic Pain 4 99.56 Very High Very High Very High
Cancer 3 97.28 Very High Very High Very High
Carcinoma 1 94.84 High High
Bone Cancer 5 91.60 High High
INFLAMMATION 1 84.28 Quite High
Nociception 1 84.16 Quite High
Pain 2 73.88 Quite High
Cancer Pain 1 49.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The mechanical allodynia was measured and the expression of spinal HMGB1 and IL-1beta was evaluated.
Negative_regulation (evaluated) of Gene_expression (expression) of HMGB1 in spinal associated with allodynia
1) Confidence 0.43 Published 2010 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 20399746 Disease Relevance 1.22 Pain Relevance 0.87

General Comments

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