INT167918

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Context Info
Confidence 0.45
First Reported 2003
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.16
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (GPER) endoplasmic reticulum (GPER) plasma membrane (GPER)
signal transducer activity (GPER)
Anatomy Link Frequency
neutrophils 2
GPER (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 34 98.96 Very High Very High Very High
agonist 3 95.28 Very High Very High Very High
tetrodotoxin 2 50.64 Quite High
halothane 8 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Catecholamine 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Nerve growth factor 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 38 98.96 Very High Very High Very High
Adhesions 46 89.52 High High
Breast Cancer 4 81.88 Quite High
Hypersensitivity 6 76.48 Quite High
Disease 2 13.12 Low Low
Asthma 6 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Salivary Gland Disease 4 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transfection and siRNA-silencing of GPR30 expression resulted in corresponding changes in GPR30 protein expression but only internally, and the response to E2 was not affected.
Positive_regulation (resulted) of Gene_expression (expression) of GPR30
1) Confidence 0.45 Published 2010 Journal J. Cell. Physiol. Section Abstract Doc Link 20432453 Disease Relevance 0.37 Pain Relevance 0.10
To investigate if a functional correlation exists between the effects of feG on CD11b and CD16 during an inflammation, these molecules were measured on blood and peritoneal neutrophils isolated from ovalbumin-sensitized rats that had been challenged with antigen after being treated with feG (100 ?
Positive_regulation (on) of Gene_expression (effects) of feG in neutrophils associated with inflammation
2) Confidence 0.05 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.18 Pain Relevance 0.05
In the dose ranges of 10-8M to 10-12M feG superoxide production remained unchanged (54.1 ± 6.7 ?
Neg (unchanged) Positive_regulation (unchanged) of Gene_expression (production) of feG
3) Confidence 0.04 Published 2003 Journal BMC Immunol Section Body Doc Link PMC152650 Disease Relevance 0.62 Pain Relevance 0

General Comments

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