INT167926

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Context Info
Confidence 0.50
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.48
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (P2rx3) Golgi apparatus (P2rx3)
Anatomy Link Frequency
neuronal 1
C8-B4 1
P2rx3 (Mus musculus)
Pain Link Frequency Relevance Heat
dorsal root ganglion 4 89.20 High High
Pain 4 75.00 Quite High
Glutamate 1 60.84 Quite High
gABA 1 60.04 Quite High
Neuropathic pain 10 58.40 Quite High
imagery 6 49.64 Quite Low
neuralgia 2 25.00 Low Low
antidepressant 35 5.00 Very Low Very Low Very Low
Endep 16 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 5 99.44 Very High Very High Very High
Sprains And Strains 4 81.16 Quite High
Ganglion Cysts 4 75.16 Quite High
Pain 4 75.00 Quite High
Nervous System Injury 3 75.00 Quite High
Neuropathic Pain 12 58.40 Quite High
Myelodysplastic Syndromes 2 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, in C58 mice there was a shift toward smaller P2X3-expressing neuronal profiles after injury, suggesting that a loss of P2X3 mRNA transcript occurred preferentially in medium-sized cells.
Transcription (transcript) of P2X3 in neuronal associated with injury
1) Confidence 0.50 Published 2010 Journal J. Peripher. Nerv. Syst. Section Abstract Doc Link 20433603 Disease Relevance 1.48 Pain Relevance 0.50
We found significant amounts of P2X3, P2X4, P2X6, and P2X7 transcripts in resting C8-B4 cells with the following relative expression levels: P2X7 > P2X4 > P2X3 > P2X6.
Transcription (transcripts) of P2X3 in C8-B4
2) Confidence 0.13 Published 2010 Journal The Journal of General Physiology Section Body Doc Link PMC2847917 Disease Relevance 0 Pain Relevance 0.06

General Comments

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