INT167975

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.18
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk9) mitochondrion (Mapk9) nucleus (Mapk9)
kinase activity (Mapk9) transcription factor binding (Mapk9) cytoplasm (Mapk9)
Anatomy Link Frequency
MDBK 2
frontal cortex 2
Mapk9 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 3 99.68 Very High Very High Very High
fluoxetine 2 94.44 High High
depression 4 88.48 High High
antidepressant 2 66.48 Quite High
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 9 99.90 Very High Very High Very High
Urological Neuroanatomy 3 98.52 Very High Very High Very High
Infection 21 96.84 Very High Very High Very High
Depression 4 88.48 High High
Viral Infection 4 65.12 Quite High
Apoptosis 64 50.00 Quite Low
Ephemeral Fever 8 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, we routinely detected JNK1 and JNK2 expression and phosphorylation in Vero cells, whereas expression of only one JNK isoform and phosphorylation could be detected in MDBK cells.
Negative_regulation (detected) of Gene_expression (expression) of JNK2 in MDBK
1) Confidence 0.02 Published 2009 Journal Veterinary Research Section Body Doc Link PMC2785050 Disease Relevance 0.16 Pain Relevance 0
Western blot study revealed that rats subjected to prenatal stress had decreased levels of p-JNK1 and p-JNK2 in the hippocampus and p-p38 in the frontal cortex, but the concentrations of p-ERK1 and p-ERK2 were not changed.
Negative_regulation (decreased) of Gene_expression (levels) of p-JNK2 in frontal cortex associated with stress, urological neuroanatomy and hippocampus
2) Confidence 0.01 Published 2010 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 20436222 Disease Relevance 1.02 Pain Relevance 0.47

General Comments

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