INT168092

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.50
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Gorasp2) molecular_function (Gorasp2)
Anatomy Link Frequency
frontal cortex 1
hippocampus 1
Gorasp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 3 98.88 Very High Very High Very High
antidepressant 3 58.00 Quite High
fluoxetine 6 56.40 Quite High
Disease Link Frequency Relevance Heat
Stress 36 99.68 Very High Very High Very High
Urological Neuroanatomy 3 99.64 Very High Very High Very High
Sprains And Strains 12 96.04 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
One consequence of early life stress is a decreased expression of glucocorticoid receptors (GRs) in the frontal cortex and hippocampus.
Gene_expression (expression) of GRs in hippocampus associated with stress, urological neuroanatomy and hippocampus
1) Confidence 0.19 Published 2010 Journal Dev. Neurosci. Section Abstract Doc Link 20453467 Disease Relevance 0.73 Pain Relevance 0.05
The present study used two inbred strains of mice that differ in their behavioral responsiveness to stress (Balb/c and C57Bl/6), exposed them to an established paradigm of early life stress (infant maternal separation), and measured their expression of frontal cortical and hippocampal GRs and the putative transcriptional activator of the GR gene, early growth response gene (egr)-1, at defined stages of postnatal development.
Gene_expression (expression) of GRs associated with stress and sprains and strains
2) Confidence 0.17 Published 2010 Journal Dev. Neurosci. Section Abstract Doc Link 20453467 Disease Relevance 1.04 Pain Relevance 0.13
One consequence of early life stress is a decreased expression of glucocorticoid receptors (GRs) in the frontal cortex and hippocampus.
Gene_expression (expression) of GRs in frontal cortex associated with stress, urological neuroanatomy and hippocampus
3) Confidence 0.07 Published 2010 Journal Dev. Neurosci. Section Abstract Doc Link 20453467 Disease Relevance 0.73 Pain Relevance 0.05

General Comments

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