INT168096

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Context Info
Confidence 0.72
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 7
Disease Relevance 7.23
Pain Relevance 8.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Cav3) Golgi apparatus (Cav3) plasma membrane organization (Cav3)
plasma membrane (Cav3) enzyme binding (Cav3) protein complex (Cav3)
Anatomy Link Frequency
spinal cords 5
Cav3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcium channel 42 100.00 Very High Very High Very High
Spinal cord 7 99.40 Very High Very High Very High
dorsal root ganglion 35 97.08 Very High Very High Very High
allodynia 7 96.80 Very High Very High Very High
Thermal hyperalgesia 21 96.24 Very High Very High Very High
Brush evoked pain 14 94.96 High High
intrathecal 7 93.52 High High
withdrawal 14 90.60 High High
Neuropathic pain 14 85.12 High High
neuralgia 14 25.00 Low Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 35 97.08 Very High Very High Very High
Neuropathic Pain 35 96.80 Very High Very High Very High
Hyperalgesia 21 96.24 Very High Very High Very High
Nociception 7 72.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Lumbar spinal cords of the rats isolated on the 5th day after the operation were prepared to measure the mRNA expression of T-type (Cav3.1, Cav3.2 and Cav3.3) calcium channel with RT-PCR methods.
Transcription (expression) of Cav3 in spinal cords associated with calcium channel
1) Confidence 0.72 Published 2010 Journal Pharmacology Section Abstract Doc Link 20453553 Disease Relevance 1.09 Pain Relevance 1.20
Compared with native and sham groups, the Cav3.2 and Cav3.3 calcium channel mRNA expression increased significantly (p < 0.05).
Transcription (expression) of Cav3 associated with calcium channel
2) Confidence 0.72 Published 2010 Journal Pharmacology Section Abstract Doc Link 20453553 Disease Relevance 0.91 Pain Relevance 1.20
Lumbar spinal cords of the rats isolated on the 5th day after the operation were prepared to measure the mRNA expression of T-type (Cav3.1, Cav3.2 and Cav3.3) calcium channel with RT-PCR methods.
Transcription (expression) of Cav3 in spinal cords associated with calcium channel
3) Confidence 0.72 Published 2010 Journal Pharmacology Section Abstract Doc Link 20453553 Disease Relevance 1.09 Pain Relevance 1.20
However, only Cav3.2 and Cav3.3 T-type calcium channel mRNA were detected in the lumbar spinal cord of rats, and there were no Cav3.1 calcium channels.
Transcription (detected) of Cav3 in spinal cord associated with calcium channel and spinal cord
4) Confidence 0.72 Published 2010 Journal Pharmacology Section Abstract Doc Link 20453553 Disease Relevance 1.04 Pain Relevance 1.29
Lumbar spinal cords of the rats isolated on the 5th day after the operation were prepared to measure the mRNA expression of T-type (Cav3.1, Cav3.2 and Cav3.3) calcium channel with RT-PCR methods.
Transcription (expression) of Cav3 in spinal cords associated with calcium channel
5) Confidence 0.72 Published 2010 Journal Pharmacology Section Abstract Doc Link 20453553 Disease Relevance 1.09 Pain Relevance 1.19
However, only Cav3.2 and Cav3.3 T-type calcium channel mRNA were detected in the lumbar spinal cord of rats, and there were no Cav3.1 calcium channels.
Transcription (detected) of Cav3 in spinal cord associated with calcium channel and spinal cord
6) Confidence 0.72 Published 2010 Journal Pharmacology Section Abstract Doc Link 20453553 Disease Relevance 1.05 Pain Relevance 1.30
Compared with native and sham groups, the Cav3.2 and Cav3.3 calcium channel mRNA expression increased significantly (p < 0.05).
Transcription (expression) of Cav3 associated with calcium channel
7) Confidence 0.72 Published 2010 Journal Pharmacology Section Abstract Doc Link 20453553 Disease Relevance 0.96 Pain Relevance 1.21

General Comments

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