INT168111

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Context Info
Confidence 0.05
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Cnr1) plasma membrane (Cnr1) cytoplasmic membrane-bounded vesicle (Dbh)
response to stress (Cnr1) signal transducer activity (Cnr1) cytoplasm (Dbh)
Dbh (Rattus norvegicus)
Cnr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 1 88.80 High High
Cannabinoid receptor 1 88.08 High High
Pain 3 84.32 Quite High
addiction 1 78.24 Quite High
Cannabinoid 4 75.00 Quite High
Endocannabinoid 1 71.12 Quite High
antagonist 1 58.96 Quite High
Disease Link Frequency Relevance Heat
Pain 3 84.32 Quite High
Dyssomnias 1 81.52 Quite High
Eating Disorder 1 80.92 Quite High
Appetite Loss 2 80.48 Quite High
Drug Dependence 1 78.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, we have developed a new drug, (R,Z)-18-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)-18-oxooctadec-9-en-7-yl phenylacetate (PhAR-DBH-Me), that appears to bind and activate the CB1R.
PhAR-DBH-Me Positive_regulation (activate) of CB1R
1) Confidence 0.05 Published 2010 Journal Bioorg. Med. Chem. Lett. Section Abstract Doc Link 20457524 Disease Relevance 0.64 Pain Relevance 0.47

General Comments

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