INT168136

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.76
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cellular_component (Hist2h4) biological_process (Hist2h4)
Anatomy Link Frequency
embryo 1
placenta 1
Hist2h4 (Mus musculus)
Pain Link Frequency Relevance Heat
headache 2 60.84 Quite High
Migraine 2 60.44 Quite High
Disease Link Frequency Relevance Heat
Sprains And Strains 4 99.68 Very High Very High Very High
Manic Depressive Disorder 2 61.72 Quite High
Migraine Disorders 2 60.84 Quite High
Epilepsy 2 60.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We observed strain differences in acetylation of histones H3 and H4 in both embryo and placenta following in utero VPA exposure, but additional studies are needed to determine the significance of these changes in mediating teratogenesis.
Localization (acetylation) of H4 in embryo associated with sprains and strains
1) Confidence 0.45 Published 2010 Journal Toxicol. Sci. Section Abstract Doc Link 20457659 Disease Relevance 0.38 Pain Relevance 0.12
We observed strain differences in acetylation of histones H3 and H4 in both embryo and placenta following in utero VPA exposure, but additional studies are needed to determine the significance of these changes in mediating teratogenesis.
Localization (acetylation) of H4 in placenta associated with sprains and strains
2) Confidence 0.15 Published 2010 Journal Toxicol. Sci. Section Abstract Doc Link 20457659 Disease Relevance 0.38 Pain Relevance 0.12

General Comments

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