INT168167

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Context Info
Confidence 0.60
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 3.48
Pain Relevance 1.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hmga1) enzyme binding (Hmga1) transcription factor binding (Hmga1)
Hmga1 (Mus musculus)
Pain Link Frequency Relevance Heat
endometriosis 28 99.72 Very High Very High Very High
anesthesia 8 70.96 Quite High
pain pelvic 2 47.84 Quite Low
Multiple sclerosis 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Demyelination 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Endometriosis 34 99.90 Very High Very High Very High
Burns 91 98.44 Very High Very High Very High
Pathologic Processes 1 90.64 High High
Hematological Disease 1 87.04 High High
Stress 13 86.60 High High
Sepsis 2 71.52 Quite High
Malignant Neoplastic Disease 2 62.00 Quite High
Reprotox - General 3 4 48.48 Quite Low
Gynecological Disease 2 45.24 Quite Low
Injury 5 14.88 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
None of the usual endometriosis cases or endometriomas had HMGA1 or HMGA2 rearrangements.
Gene_expression (rearrangements) of HMGA1 associated with endometriosis
1) Confidence 0.60 Published 2010 Journal Genes Chromosomes Cancer Section Abstract Doc Link 20461755 Disease Relevance 1.29 Pain Relevance 0.48
In conclusion, mass-forming endometriosis is an uncommon subset of endometriosis that harbors HMGA1 or HMGA2 rearrangements in up to 29% of cases.
Gene_expression (rearrangements) of HMGA1 associated with endometriosis
2) Confidence 0.60 Published 2010 Journal Genes Chromosomes Cancer Section Abstract Doc Link 20461755 Disease Relevance 1.24 Pain Relevance 0.47
These include binding sites for HMGA1/2, C/EBP?
Gene_expression (/) of HMGA1
3) Confidence 0.51 Published 2007 Journal BMC Genomics Section Body Doc Link PMC2241634 Disease Relevance 0.96 Pain Relevance 0.13

General Comments

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