INT168189

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Context Info
Confidence 0.20
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PLXNA2) intracellular (PLXNA2)
PLXNA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 1 97.48 Very High Very High Very High
Pain matrix 2 93.44 High High
Glutamate 1 86.48 High High
Migraine 5 85.56 High High
Neurotransmitter 2 81.36 Quite High
Inflammation 1 59.60 Quite High
Disease Link Frequency Relevance Heat
Pain 2 93.16 High High
Headache 5 85.56 High High
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This hypothesis derived from the results of the biochemical studies, mainly generated from our laboratory, on the possible metabolic shifts of tyrosine toward an activation of decarboxylase enzyme activity with an increased synthesis of traces amines, i.e. tyr, oct and syn, and an unphysiological synthesis of noradrenalin and dopamine.
Spec (possible) Positive_regulation (activation) of oct associated with dopamine
1) Confidence 0.20 Published 2010 Journal Neurol. Sci. Section Abstract Doc Link 20464574 Disease Relevance 0.49 Pain Relevance 0.75

General Comments

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