INT168235

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Context Info
Confidence 0.52
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Nfib) nucleus (Nfib) DNA binding (Nfib)
Anatomy Link Frequency
IVD 1
Nfib (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 1 99.24 Very High Very High Very High
Pain 1 79.68 Quite High
Chronic low back pain 1 67.20 Quite High
Disease Link Frequency Relevance Heat
Neck Pain 1 79.68 Quite High
Intervertebral Disk Degeneration 1 75.00 Quite High
Low Back Pain 1 67.20 Quite High
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment of FFQSP for one month prevented the histological changes indicating IVD disorganization; increased type II-collagen level, decreased type X-collagen protein level, and increased Col2alpha1 mRNA expression at all time points; and decreased Col10alpha1, matrix metalloproteinase (MMP)-3, MMP13, and Interleukin (IL)-1beta mRNA expression induced by upright posture for 7 and 9 months.
Transcription (expression) of 1beta in IVD associated with metalloproteinase
1) Confidence 0.52 Published 2010 Journal J. Pharmacol. Sci. Section Abstract Doc Link 20472983 Disease Relevance 0.22 Pain Relevance 0.20

General Comments

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