INT168323

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Gsta5 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
MU agonist 1 97.64 Very High Very High Very High
Oxycodone 4 97.16 Very High Very High Very High
Opioid 1 92.80 High High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Repeated administration of oxycodone modifies the gene expression of several drug metabolising enzymes in the hepatic tissue of male Sprague-Dawley rats, including glutathione S-transferase A-5 (rGSTA5) and CYP3A2.
Positive_regulation (transferase) of Gene_expression (transferase) of rGSTA5 associated with oxycodone
1) Confidence 0.15 Published 2010 Journal J. Pharm. Pharmacol. Section Title Doc Link 20487198 Disease Relevance 0 Pain Relevance 0.56

General Comments

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