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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Cyp3a2) endoplasmic reticulum (Cyp3a2) enzyme binding (Cyp3a2)
cytoplasm (Cyp3a2)
Cyp3a2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Oxycodone 4 50.00 Quite Low
MU agonist 1 5.00 Very Low Very Low Very Low
Opioid 1 5.00 Very Low Very Low Very Low


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: Repeated oxycodone administration is associated with a significant up-regulation of rGSTA5 and concomitant down-regulation of CYP3A2 mRNA, protein expression and functionality.
Regulation (regulation) of Transcription (expression) of CYP3A2
1) Confidence 0.45 Published 2010 Journal J. Pharm. Pharmacol. Section Body Doc Link 20487198 Disease Relevance 0 Pain Relevance 0

General Comments

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