INT168374

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Context Info
Confidence 0.50
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 4
Disease Relevance 5.09
Pain Relevance 1.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Capns1) cytoplasm (Capns1)
Anatomy Link Frequency
wing 1
Capns1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
corticosteroid 114 98.80 Very High Very High Very High
withdrawal 9 97.04 Very High Very High Very High
anesthesia 3 96.88 Very High Very High Very High
local anesthetic 3 91.92 High High
Action potential 1 82.56 Quite High
nerve block 2 75.00 Quite High
analgesia 2 75.00 Quite High
lidocaine 1 71.56 Quite High
Inflammation 39 69.92 Quite High
ischemia 3 62.00 Quite High
Disease Link Frequency Relevance Heat
Syndrome 567 100.00 Very High Very High Very High
Asthma 234 99.68 Very High Very High Very High
Occupational Lung Diseases 21 84.24 Quite High
Sinusitis 9 83.52 Quite High
Rhinitis 27 82.72 Quite High
Hypersensitivity 24 81.28 Quite High
Rare Diseases 3 79.44 Quite High
Increased Venous Pressure Under Development 69 79.04 Quite High
Disease 48 75.84 Quite High
Vasculitis 9 74.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No technique significantly decreased CDPs or resulted in consistent wing droop.
Negative_regulation (decreased) of CDPs in wing
1) Confidence 0.50 Published 2010 Journal J. Avian Med. Surg. Section Abstract Doc Link 20496603 Disease Relevance 0 Pain Relevance 0.88
In contrast, 17 (32%) patients are classified in category B and after receiving a LTRA, developed CSS during the tapering or discontinuation of GCS therapy.
Negative_regulation (developed) of CSS associated with syndrome
2) Confidence 0.01 Published 2005 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661620 Disease Relevance 1.20 Pain Relevance 0
This further supports the theory that some asthmatic patients might have preexisting CSS that is suppressed during asthma treatment with corticosteroids.


Negative_regulation (suppressed) of CSS associated with asthma, corticosteroid and syndrome
3) Confidence 0.01 Published 2005 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661620 Disease Relevance 1.95 Pain Relevance 0.05
Hence, it is unknown if CSS is a direct effect of LT inhibition or if it is due to preexisting CSS being unmasked as a result of steroid withdrawal.
Negative_regulation (inhibition) of CSS associated with syndrome and withdrawal
4) Confidence 0.01 Published 2005 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC1661620 Disease Relevance 1.94 Pain Relevance 0.18

General Comments

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