INT168427

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.53
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

DNA binding (RYBP, Nfkb1) cytoplasm (RYBP, Nfkb1) nucleus (RYBP, Nfkb1)
nucleoplasm (RYBP) mitochondrion (Nfkb1) intracellular (RYBP)
Anatomy Link Frequency
liver 2
RYBP (Homo sapiens)
Nfkb1 (Mus musculus)
Pain Link Frequency Relevance Heat
Paracetamol 6 75.00 Quite High
Disease Link Frequency Relevance Heat
Toxicity 2 78.72 Quite High
Hepatotoxicity 2 75.00 Quite High
Acute Liver Failure 2 58.56 Quite High
Overdose 2 54.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemical or immunofluorescent examinations in the liver tissue generally support these findings, suggesting that PGE2 inhibited APAP-induced activation of nuclear factor kappa B (NF-kappaB).
APAP Positive_regulation (activation) of NF-kappaB in liver
1) Confidence 0.01 Published 2010 Journal Histol. Histopathol. Section Abstract Doc Link 20503171 Disease Relevance 0.27 Pain Relevance 0.19
Immunohistochemical or immunofluorescent examinations in the liver tissue generally support these findings, suggesting that PGE2 inhibited APAP-induced activation of nuclear factor kappa B (NF-kappaB).
APAP Positive_regulation (activation) of nuclear factor kappa B in liver
2) Confidence 0.01 Published 2010 Journal Histol. Histopathol. Section Abstract Doc Link 20503171 Disease Relevance 0.27 Pain Relevance 0.19

General Comments

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