INT168479

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Context Info
Confidence 0.36
First Reported 2006
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 13
Total Number 13
Disease Relevance 10.68
Pain Relevance 4.21

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protein folding (BAG3) cytosol (BAG3) plasma membrane (BAG3)
cytoplasm (BAG3)
Anatomy Link Frequency
facets 1
BAG3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 952 100.00 Very High Very High Very High
Electroencephalography 72 100.00 Very High Very High Very High
Opioid 1 95.32 Very High Very High Very High
Neurotransmitter 10 51.00 Quite High
Dopamine 18 49.68 Quite Low
addiction 5 32.84 Quite Low
opiate 1 31.20 Quite Low
drug abuse 2 29.60 Quite Low
alcohol 2 29.04 Quite Low
anticonvulsant 1 18.80 Low Low
Disease Link Frequency Relevance Heat
Cv General 3 Under Development 931 100.00 Very High Very High Very High
Brain Injury 182 98.88 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 80 94.88 High High
Injury 84 92.32 High High
Emergencies 7 91.24 High High
Death 28 87.60 High High
Sleep Disorders 21 83.60 Quite High
Brain Death 7 76.72 Quite High
Sprains And Strains 1 76.32 Quite High
Coma 30 75.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No overall association between BIS and Svo2 was observed, either in unadjusted analysis or adjusted for covariates.
BIS Neg (No) Binding (association) of
1) Confidence 0.36 Published 2010 Journal Anesthesiology Section Body Doc Link 20508497 Disease Relevance 0 Pain Relevance 0
CONCLUSIONS: In patients undergoing cardiopulmonary bypass, we found no overall association between BIS and Svo2.
BIS Neg (no) Binding (association) of
2) Confidence 0.36 Published 2010 Journal Anesthesiology Section Body Doc Link 20508497 Disease Relevance 0 Pain Relevance 0
In data points with temperatures less than the median (T < 34.1 degrees C), a significant association between BIS and Svo2 was observed both in unadjusted (beta = -0.32, P = 0.01) and adjusted (beta = -0.27, P = 0.04) analyses.
BIS Binding (association) of
3) Confidence 0.36 Published 2010 Journal Anesthesiology Section Body Doc Link 20508497 Disease Relevance 0 Pain Relevance 0
A weak but statistically significant association between BIS and Svo2 was observed in patients with temperatures less than 34.1 degrees C.
BIS Binding (association) of
4) Confidence 0.36 Published 2010 Journal Anesthesiology Section Body Doc Link 20508497 Disease Relevance 0 Pain Relevance 0
Survival is independently associated with BIS, StcO2, ICP, and CPP.
BIS Binding (associated) of associated with cva
5) Confidence 0.28 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.38 Pain Relevance 0.54
Good neurological outcome is also independently associated with BIS, StcO2, ICP, and CPP.
BIS Binding (associated) of associated with cva
6) Confidence 0.28 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.37 Pain Relevance 0.53
With a BIS <60 and StcO2 <70 an ICP monitor is indicated.
BIS Binding (indicated) of associated with cva
7) Confidence 0.24 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.97 Pain Relevance 0.59
When comparing the surviving and nonsurviving patients, the mean difference is much greater for the CAP Index than it is for ICP, CPP, StcO2, and BIS.
BIS Binding (is) of associated with cva
8) Confidence 0.24 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.42 Pain Relevance 0.57
The multiple associations of BIS and StcO2 with survival, neurological outcome, ICP, and CPP suggest that BIS and StcO2 are clinically discriminate parameters.
BIS Binding (associations) of associated with cva
9) Confidence 0.24 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.06 Pain Relevance 0.53
The independent association of BIS, StcO2, and ICP with outcomes indicates that BIS, StcO2, and ICP data are complementary.
BIS Binding (association) of associated with cva
10) Confidence 0.24 Published 2006 Journal Crit Care Section Body Doc Link PMC1794465 Disease Relevance 1.27 Pain Relevance 0.56
Survival and good outcome are independently associated with BIS ?
BIS Binding (associated) of
11) Confidence 0.23 Published 2006 Journal Crit Care Section Abstract Doc Link PMC1794465 Disease Relevance 1.37 Pain Relevance 0.49
The BIS and EIQ are highly correlated and theoretically related scales, however they are associated with different neural activation profiles in a behavioral inhibition task [77], suggesting that they assess distinct facets of impulsivity.
BIS Binding (associated) of in facets associated with attention deficit hyperactivity disorder
12) Confidence 0.04 Published 2007 Journal Behav Brain Funct Section Body Doc Link PMC1781951 Disease Relevance 0.83 Pain Relevance 0.03
Furthermore, the BIS and other heuristic EEG monitoring approaches have been reported to be blind to the effects of a number of anaesthetic agents which are in routine clinical use, including nitrous oxide and the opioids (e.g.
BIS Binding (blind) of associated with opioid and electroencephalography
13) Confidence 0.02 Published 2008 Journal Cogn Neurodyn Section Body Doc Link PMC2585619 Disease Relevance 0 Pain Relevance 0.39

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