INT168513

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Context Info
Confidence 0.22
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prkaca, Trpv1) plasma membrane (Prkaca, Trpv1) nucleoplasm (Prkaca)
mitochondrion (Prkaca) Golgi apparatus (Prkaca) protein complex (Prkaca)
Anatomy Link Frequency
primary sensory neurons 2
Prkaca (Rattus norvegicus)
Trpv1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 1 86.64 High High
Cannabinoid 2 75.00 Quite High
adenocard 1 61.76 Quite High
Hyperalgesia 1 56.84 Quite High
Inflammation 1 56.12 Quite High
nociceptor 1 54.24 Quite High
Endocannabinoid 1 25.00 Low Low
qutenza 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 1 56.84 Quite High
INFLAMMATION 1 56.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings suggest that activation of the CB1 receptor can reduce the activity of TRPV1 in primary sensory neurons, and that this inhibitory effect could be mediated through the reduction of PKA-mediated phosphorylation of TRPV1.
PKA Positive_regulation (mediated) of Phosphorylation (phosphorylation) of TRPV1 in primary sensory neurons
1) Confidence 0.22 Published 2010 Journal Acta Physiol Hung Section Abstract Doc Link 20511124 Disease Relevance 0.11 Pain Relevance 0.29

General Comments

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