INT168534

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Context Info
Confidence 0.38
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.64
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grik5) plasma membrane (Grik5) cell (Grik5)
Anatomy Link Frequency
substantia gelatinosa 1
Grik5 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinothalamic tract neurons 1 99.68 Very High Very High Very High
Spinal cord 1 98.44 Very High Very High Very High
Hippocampus 3 97.48 Very High Very High Very High
substantia gelatinosa 7 96.48 Very High Very High Very High
Glutamate receptor 11 95.08 Very High Very High Very High
Glutamate 6 85.76 High High
Root ganglion neuron 1 82.24 Quite High
amygdala 120 74.24 Quite High
Pyramidal cell 25 71.16 Quite High
GABAergic 17 69.52 Quite High
Disease Link Frequency Relevance Heat
Nociception 1 92.04 High High
Anxiety Disorder 50 82.92 Quite High
Ganglion Cysts 1 81.84 Quite High
Targeted Disruption 12 65.96 Quite High
Panic Disorder 1 63.72 Quite High
Schizophrenia 13 50.00 Quite Low
Urological Neuroanatomy 1 31.08 Quite Low
Disease 11 17.76 Low Low
Pain 3 5.00 Very Low Very Low Very Low
Aids-related Complex 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The KA receptor family is composed of five different subunits, namely GluR5, GluR6, GluR7, KA1 and KA2, which can form a variety of homomeric and heteromeric receptors [21].
Gene_expression (composed) of KA2
1) Confidence 0.38 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1766473 Disease Relevance 0.55 Pain Relevance 0.52
Also, we observed that the two-step procedure unmasked core interacting proteins that were not detected by mass spectrometry in the single-step purification: Ten known PSD-95 interactors, Begain, Cit, Grik2, Grik5, Grin2c, Kcna4, Lrp1, Nlgn2, Nlgn3 and Shank1, were present only after the tandem purification.
Gene_expression (present) of Grik5
2) Confidence 0.32 Published 2009 Journal Mol Syst Biol Section Body Doc Link PMC2694677 Disease Relevance 0 Pain Relevance 0.03
Postnatal change of GluR5 kainate receptor expression in the substantia gelatinosa neuron of the trigeminal subnucleus caudalis in mice.
Gene_expression (expression) of GluR5 kainate receptor in substantia gelatinosa associated with spinothalamic tract neurons
3) Confidence 0.05 Published 2010 Journal Brain Res. Section Title Doc Link 20513362 Disease Relevance 0.09 Pain Relevance 0.34

General Comments

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