INT168538

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.72
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.76
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Hsd17b12) endoplasmic reticulum (Hsd17b12) extracellular matrix organization (Hsd17b12)
Anatomy Link Frequency
neurons 1
dorsal horn 1
Hsd17b12 (Mus musculus)
Pain Link Frequency Relevance Heat
Dorsal horn 11 99.54 Very High Very High Very High
substantia gelatinosa 71 99.16 Very High Very High Very High
antagonist 10 98.32 Very High Very High Very High
Lasting pain 2 97.28 Very High Very High Very High
gABA 12 91.56 High High
spinal dorsal horn 5 88.08 High High
agonist 6 85.40 High High
Pain 3 81.52 Quite High
Spinothalamic tract neurons 2 75.00 Quite High
Spinal cord 18 65.84 Quite High
Disease Link Frequency Relevance Heat
Pain 5 97.28 Very High Very High Very High
Anxiety Disorder 1 96.32 Very High Very High Very High
Epilepsy 1 96.08 Very High Very High Very High
Nociception 9 93.36 High High
Targeted Disruption 4 87.04 High High
Overdose 1 5.00 Very Low Very Low Very Low
Congenital Anomalies 1 5.00 Very Low Very Low Very Low
Inflammatory Pain 1 5.00 Very Low Very Low Very Low
Disseminated Intravascular Coagulation 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results show that the GluR5 KAR subunits are expressed functionally on the SG neurons of the Vc in mice, and the expression levels of the GluR5 subunits decrease with postnatal development.
Gene_expression (expressed) of GluR5 KAR in neurons associated with substantia gelatinosa
1) Confidence 0.72 Published 2010 Journal Brain Res. Section Abstract Doc Link 20513362 Disease Relevance 0.06 Pain Relevance 0.48
Five different KAR subunits have been cloned and the expression of the KAR subunits showed developmental changes.
Gene_expression (expression) of KAR
2) Confidence 0.63 Published 2010 Journal Brain Res. Section Abstract Doc Link 20513362 Disease Relevance 0.09 Pain Relevance 0.29
Our previous results in dorsal horn slices found that the KAR-mediated current can only be elicited upon the stimulation of the afferent axon at an intensity strong enough to activate high threshold A?
Gene_expression (elicited) of KAR in dorsal horn associated with dorsal horn
3) Confidence 0.18 Published 2006 Journal Mol Pain Section Body Doc Link PMC1570342 Disease Relevance 0.61 Pain Relevance 0.61

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox