INT168607

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Context Info
Confidence 0.23
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.45
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Nos1) extracellular matrix organization (Mmp9) enzyme binding (Nos1)
protein complex (Mmp9) cytoplasm (Nos1) cytosol (Nos1)
Nos1 (Mus musculus)
Mmp9 (Mus musculus)
Pain Link Frequency Relevance Heat
withdrawal 5 99.82 Very High Very High Very High
Morphine 10 99.60 Very High Very High Very High
addiction 4 93.04 High High
allodynia 1 91.32 High High
metalloproteinase 2 75.00 Quite High
Physical dependence 2 75.00 Quite High
Dorsal horn 1 72.20 Quite High
tolerance 2 71.52 Quite High
Opioid 3 63.44 Quite High
narcan 2 60.76 Quite High
Disease Link Frequency Relevance Heat
Morphine Dependence 2 93.76 High High
Neuropathic Pain 1 91.32 High High
Drug Dependence 2 75.00 Quite High
Opiate Addiction 2 50.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Morphine withdrawal-induced MMP-9 activity is also reduced by an nNOS inhibitor.
Negative_regulation (inhibitor) of nNOS Negative_regulation (reduced) of MMP-9 associated with withdrawal and morphine
1) Confidence 0.23 Published 2010 Journal J. Neurosci. Section Abstract Doc Link 20519536 Disease Relevance 0.45 Pain Relevance 1.61

General Comments

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