INT168618

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Context Info
Confidence 0.53
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.55
Pain Relevance 0.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Cort)
Anatomy Link Frequency
plasma 2
PGE2 2
Cort (Rattus norvegicus)
Pain Link Frequency Relevance Heat
electroacupuncture 91 99.98 Very High Very High Very High
Hyperalgesia 14 79.68 Quite High
Inflammation 25 79.00 Quite High
Inflammatory response 2 57.28 Quite High
Inflammatory stimuli 1 50.00 Quite Low
Acupuncture 13 42.92 Quite Low
withdrawal 2 30.72 Quite Low
Osteoarthritis 1 26.80 Quite Low
antagonist 4 11.92 Low Low
nociceptor 1 10.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 16 79.68 Quite High
INFLAMMATION 28 79.00 Quite High
Shock 1 68.20 Quite High
Stress 7 65.20 Quite High
Pressure And Volume Under Development 18 50.00 Quite Low
Knee Osteoarthritis 1 26.80 Quite Low
Disease 4 21.96 Low Low
Pain 2 5.00 Very Low Very Low Very Low
Hypertension 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CONCLUSIONS: Our results suggest that the administration of exogenous estradiol may mediate inflammatory responses by regulating the levels of PGE2 and/or CORT release, thereby mediating the nociceptive response to an inflammatory stimulus.


Regulation (regulating) of Localization (release) of CORT in PGE2
1) Confidence 0.53 Published 2010 Journal Ethn Dis Section Body Doc Link 20521385 Disease Relevance 0 Pain Relevance 0
In Experiment 1 we measured CORT plasma levels to see if EA regulates CORT secretion.
Regulation (regulates) of Localization (secretion) of CORT in plasma associated with electroacupuncture
2) Confidence 0.30 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC1976320 Disease Relevance 0.55 Pain Relevance 0.64

General Comments

This test has worked.

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