INT168659

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (SRI) transport (SRI) plasma membrane (SRI)
intracellular (SRI) cytoplasm (SRI)
Anatomy Link Frequency
SCN 2
SRI (Homo sapiens)
Pain Link Frequency Relevance Heat
fluoxetine 6 99.32 Very High Very High Very High
Serotonin 6 98.50 Very High Very High Very High
Neuropeptide 3 75.88 Quite High
Disease Link Frequency Relevance Heat
Aging 5 84.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because serotonin innervation trophically supports SCN VIP mRNA expression, and serotonin transporters decrease extracellular serotonin, we predicted that chronic administration of the serotonin-selective reuptake inhibitor, fluoxetine, would attenuate the age-related changes in SCN VIP mRNA expression and 5-HT(1B) receptors.
Regulation (changes) of Transcription (expression) of SCN in SCN associated with serotonin and fluoxetine
1) Confidence 0.01 Published 2010 Journal Eur. J. Neurosci. Section Abstract Doc Link 20525077 Disease Relevance 0.30 Pain Relevance 0.68

General Comments

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