INT168681

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Context Info
Confidence 0.37
First Reported 2006
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.70
Pain Relevance 1.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (BMS1) nucleus (BMS1) GTPase activity (BMS1)
Anatomy Link Frequency
mouth 2
white blood cells 1
EHS 1
BMS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Nav1.7 43 100.00 Very High Very High Very High
sodium channel 17 100.00 Very High Very High Very High
pulpitis 12 100.00 Very High Very High Very High
Face pain 11 100.00 Very High Very High Very High
IPN 7 100.00 Very High Very High Very High
agonist 1 100.00 Very High Very High Very High
Pain 64 96.12 Very High Very High Very High
cva 1 63.72 Quite High
Inflammation 9 25.96 Quite Low
Inflammatory mediators 1 25.28 Quite Low
Disease Link Frequency Relevance Heat
Cancer 43 100.00 Very High Very High Very High
Burning Mouth Syndrome 40 100.00 Very High Very High Very High
Pulpitis 12 100.00 Very High Very High Very High
Facial Pain 11 100.00 Very High Very High Very High
Inflammatory Pain 7 100.00 Very High Very High Very High
Necrosis 1 100.00 Very High Very High Very High
Neuropathic Pain 12 99.36 Very High Very High Very High
Diabetes Mellitus 7 98.76 Very High Very High Very High
Sarcoma 1 97.76 Very High Very High Very High
Pain 49 96.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
AIMS AND OBJECTIVES: To study Na v 1.7 levels in dental pulpitis pain, an inflammatory condition, and burning mouth syndrome (BMS), considered a neuropathic orofacial pain disorder.
Gene_expression (levels) of BMS in mouth
1) Confidence 0.37 Published 2010 Journal BMC Neurosci Section Body Doc Link 20529324 Disease Relevance 0.10 Pain Relevance 0
The concentration of xylitol in bronchial ASL collected by the BMS probe was at least one log higher than the BAL concentration after correcting for dilution.
Gene_expression (probe) of BMS
2) Confidence 0.36 Published 2006 Journal Respir Res Section Body Doc Link PMC1386668 Disease Relevance 0.05 Pain Relevance 0
Our study aimed to investigate and compare the expression of Nav1.7 sodium channel within two orofacial pain disorders, an inflammatory pain condition dental pulpitis, and burning mouth syndrome (BMS), considered a neuropathic condition.
Spec (investigate) Gene_expression (expression) of BMS in mouth associated with pulpitis, ipn, face pain, neuropathic pain, burning mouth syndrome, sodium channel and nav1.7
3) Confidence 0.05 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2890014 Disease Relevance 1.15 Pain Relevance 1.54
EHS mouse tumors produce a homogenous interstitial matrix of basement membrane material, making EHS interstitial matrix a typical in vitro model for physiological BMs which are usually too thin for content analysis [128], [129].
Gene_expression (produce) of BMs in EHS associated with cancer
4) Confidence 0.04 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2663039 Disease Relevance 0.30 Pain Relevance 0
BMS-663513 is a fully humanized monoclonal antibody agonist of CD-137, a tumor necrosis factor (TNF)-receptor that is expressed on the surfaces of activated white blood cells.
Gene_expression (expressed) of BMS-663513 in white blood cells associated with necrosis, cancer and agonist
5) Confidence 0.02 Published 2008 Journal J Hematol Oncol Section Body Doc Link PMC2647552 Disease Relevance 1.11 Pain Relevance 0.08

General Comments

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