INT168682

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Context Info
Confidence 0.36
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.84
Pain Relevance 1.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NDRG1) plasma membrane (NDRG1) nucleus (NDRG1)
cytoplasm (NDRG1)
Anatomy Link Frequency
neuron 1
NDRG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
sodium channel 3 99.24 Very High Very High Very High
Pain 12 98.48 Very High Very High Very High
antagonist 10 96.68 Very High Very High Very High
Nav1.7 6 93.72 High High
Congenital analgesia 1 88.12 High High
nav1.8 3 85.64 High High
hyperexcitability 2 81.08 Quite High
Inflammation 6 34.84 Quite Low
Cannabinoid receptor 1 21.60 Low Low
corticosteroid 1 21.36 Low Low
Disease Link Frequency Relevance Heat
Pain 12 98.48 Very High Very High Very High
Syndrome 1 90.12 High High
Congenital Pain Insensitivity 1 88.12 High High
Mental Disorders 12 79.76 Quite High
Disease 15 78.08 Quite High
Inflammatory Bowel Disease 1 35.40 Quite Low
Functional Bowel Disorder 2 19.88 Low Low
Obesity 5 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Emergencies 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The actual base rate of the G-DRG-system has not yet been set and might be below € 2,900.
Localization (rate) of G-DRG-system
1) Confidence 0.36 Published 2004 Journal GMS Psycho-Social Medicine Section Body Doc Link PMC2736487 Disease Relevance 0.22 Pain Relevance 0
Effects of ranolazine on wild-type and mutant hNav1.7 channels and on DRG neuron excitability.
Localization (excitability) of DRG in neuron
2) Confidence 0.17 Published 2010 Journal Mol Pain Section Title Doc Link 20529343 Disease Relevance 0.61 Pain Relevance 1.40
We tested for the possible involvement of the IP3 receptor in the Echinacea-induction of intracellular Ca2+ release by evaluating the effect of 2-aminoethoxydiphenyl borate (2-APB), an IP3 receptor antagonist, on Echinacea-induced cytosolic Ca2+ increase.
Localization (release) of Echinacea-induction associated with antagonist
3) Confidence 0.01 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC3002894 Disease Relevance 0 Pain Relevance 0.05

General Comments

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