INT168723

Context Info Confidence 0.48 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Title Documents 1 Total Number 1 Disease Relevance 1.10 Pain Relevance 1.84

aging (Calca) intracellular (Calca) cytoplasm (Calca) lipid metabolic process (Trpv1) cytosol (Trpv1) extracellular space (Calca)

Anatomy Link Frequency dorsal root ganglion 3 Trpv1 (Rattus norvegicus) Calca (Rattus norvegicus)

Pain Link Frequency Relevance Heat Calcitonin gene-related peptide 11 100.00 Inflammation 8 99.90 Pain 5 99.90 Root ganglion neuron 1 99.56 IPN 3 96.60 nociceptor 2 86.24 Thermal hyperalgesia 1 74.76 dorsal root ganglion 5 72.60 antagonist 1 67.60

Disease Link Frequency Relevance Heat Ganglion Cysts 6 99.36 Inflammatory Pain 3 96.60 INFLAMMATION 4 90.96 Pain 1 85.48 Hyperalgesia 1 74.76 Nociception 1 58.16

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Acid activation of Trpv1 leads to an up-regulation of calcitonin gene-related peptide expression in dorsal root ganglion neurons via the CaMK-CREB cascade: a potential mechanism of inflammatory pain.

Positive_regulation (activation) of Trpv1 in dorsal root ganglion Positive_regulation (up-regulation) of Gene_expression (expression) of calcitonin gene-related peptide in dorsal root ganglion associated with ganglion cysts, inflammation, ipn, root ganglion neuron and calcitonin gene-related peptide

1) Confidence 0.48 Published 2010 Journal Mol. Biol. Cell Section Title Doc Link 20534813 Disease Relevance 1.10 Pain Relevance 1.84

General Comments

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