INT168821

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.71
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Mir200b (Mus musculus)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 2 79.52 Quite High
Disease Link Frequency Relevance Heat
Pancreatic Cancer 20 99.98 Very High Very High Very High
Cancer 2 95.16 Very High Very High Very High
Pancreatitis 2 79.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, most pancreatic cancers express miR-200a and miR-200b, but this expression does not affect SIP1 expression, as the SIP1 promoter is silenced by hypermethylation and in these cancers E-cadherin is generally expressed.
Gene_expression (express) of miR-200b associated with cancer and pancreatic cancer
1) Confidence 0.01 Published 2010 Journal Cancer Res. Section Abstract Doc Link 20551052 Disease Relevance 0.87 Pain Relevance 0.08
In Panc-1 cells, which express SIP1, have low E-cadherin expression, and do not express miR-200a or miR-200b, treatment with miR-200a and miR-200b downregulated SIP1 mRNA and increased E-cadherin expression.
Gene_expression (express) of miR-200b
2) Confidence 0.01 Published 2010 Journal Cancer Res. Section Abstract Doc Link 20551052 Disease Relevance 0.84 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox