INT168828

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.67
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (DDB1, UBR1) cytosol (UBR1) nucleoplasm (DDB1)
nucleus (DDB1) DNA binding (DDB1) ligase activity (UBR1)
DDB1 (Homo sapiens)
UBR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
member 8 2 96.64 Very High Very High Very High
Disease Link Frequency Relevance Heat
Necrosis 2 97.94 Very High Very High Very High
Cancer 8 97.76 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We characterize a new Myc-interacting factor, TRPC4AP (transient receptor potential cation channel, subfamily C, member 4-associated protein)/TRUSS (tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein), which is the receptor for a DDB1 (damage-specific DNA-binding protein 1)-CUL4 (Cullin 4) E3 ligase complex for selective Myc degradation through the proteasome.
DDB1 Binding (complex) of ligase associated with necrosis, cancer and member 8
1) Confidence 0.00 Published 2010 Journal Genes Dev. Section Abstract Doc Link 20551172 Disease Relevance 0.34 Pain Relevance 0.10
We characterize a new Myc-interacting factor, TRPC4AP (transient receptor potential cation channel, subfamily C, member 4-associated protein)/TRUSS (tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein), which is the receptor for a DDB1 (damage-specific DNA-binding protein 1)-CUL4 (Cullin 4) E3 ligase complex for selective Myc degradation through the proteasome.
DDB1 Binding (complex) of ligase associated with necrosis, cancer and member 8
2) Confidence 0.00 Published 2010 Journal Genes Dev. Section Abstract Doc Link 20551172 Disease Relevance 0.34 Pain Relevance 0.10

General Comments

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