INT16887

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.41
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 10
Total Number 10
Disease Relevance 2.32
Pain Relevance 4.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Maoa) oxidoreductase activity (Maoa)
Anatomy Link Frequency
brain 2
Maoa (Mus musculus)
Pain Link Frequency Relevance Heat
monoamine 62 100.00 Very High Very High Very High
butorphanol 8 100.00 Very High Very High Very High
anesthesia 4 99.78 Very High Very High Very High
noradrenaline 16 98.20 Very High Very High Very High
dopamine receptor 6 97.60 Very High Very High Very High
Serotonin 58 97.48 Very High Very High Very High
antagonist 8 96.88 Very High Very High Very High
Dopamine 112 95.80 Very High Very High Very High
depression 130 95.36 Very High Very High Very High
Catechol-O-methyltransferase 93 94.64 High High
Disease Link Frequency Relevance Heat
Manic Depressive Disorder 13 98.84 Very High Very High Very High
Attention Deficit Hyperactivity Disorder 54 98.24 Very High Very High Very High
Pressure And Volume Under Development 3 97.36 Very High Very High Very High
Depression 163 95.36 Very High Very High Very High
Reprotox - General 2 2 85.12 High High
Aggression 11 82.48 Quite High
Anxiety Disorder 12 78.28 Quite High
Sprains And Strains 57 66.36 Quite High
Targeted Disruption 23 65.36 Quite High
Pressure Volume 2 Under Development 1 63.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This role of MAOA in alerting may be related to the findings of Lim et al., [72] showing a significant association of the MAOA locus to susceptibility for bipolar disorder.
MAOA Binding (association) of associated with manic depressive disorder
1) Confidence 0.41 Published 2002 Journal BMC Neurosci Section Body Doc Link PMC130047 Disease Relevance 0.47 Pain Relevance 0.40
Interaction of butorphanol, with monoamine oxidase inhibitor, tranylcypromine.
monoamine oxidase Binding (Interaction) of associated with butorphanol and monoamine
2) Confidence 0.37 Published 1991 Journal Forensic Sci. Int. Section Title Doc Link 1855717 Disease Relevance 0.20 Pain Relevance 1.27
RS-2232, a compound with a reversible and specific type-A monoamine oxidase inhibiting property in mouse brain.
monoamine oxidase Binding (compound) of in brain associated with anesthesia and monoamine
3) Confidence 0.37 Published 1987 Journal Jpn. J. Pharmacol. Section Title Doc Link 3682407 Disease Relevance 0 Pain Relevance 0.20
Measurement of MAO-A and MAO-B activities
MAO Binding (activities) of
4) Confidence 0.29 Published 2008 Journal Indian Journal of Pharmacology Section Body Doc Link PMC2792615 Disease Relevance 0 Pain Relevance 0.09
Because of its metabolic role, drugs which interfere with MAOA such as clorgyline have been used to treat ADHD [64].
MAOA Binding (interfere) of associated with attention deficit hyperactivity disorder
5) Confidence 0.28 Published 2002 Journal BMC Neurosci Section Body Doc Link PMC130047 Disease Relevance 0.73 Pain Relevance 0.40
Polymorphisms in MAOA were found to be associated with executive attention.
MAOA Binding (associated) of
6) Confidence 0.28 Published 2002 Journal BMC Neurosci Section Body Doc Link PMC130047 Disease Relevance 0.34 Pain Relevance 0.39
As expected, dopaminergic systems are clearly downstream of Comt, including Maoa in the striatum, DRD1 and DRD2 binding density in multiple brain regions, and the response to the dopamine receptor antagonist haloperidol.
Maoa Binding (binding) of in brain associated with antagonist and dopamine receptor
7) Confidence 0.27 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923157 Disease Relevance 0.07 Pain Relevance 0.44
Neither MAO-B specific (RO 16 6491) nor mixed MAO inhibitors (nialamide and pargyline) interacted with GLY to produce antiimmobility effects.
MAO Binding (interacted) of
8) Confidence 0.26 Published 1996 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 8853196 Disease Relevance 0 Pain Relevance 0.30
Tranylcypromine irreversibly and nonselectively binds to MAO-A and MAO-B.
MAO Binding (binds) of
9) Confidence 0.20 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2845130 Disease Relevance 0.26 Pain Relevance 0.51
Tranylcypromine irreversibly and nonselectively binds to MAO-A and MAO-B.
MAO Binding (binds) of
10) Confidence 0.20 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2845130 Disease Relevance 0.25 Pain Relevance 0.48

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox