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Context Info
Confidence 0.40
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Igf1r)
Anatomy Link Frequency
heart 2
Igf1r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory marker 2 86.56 High High
anesthesia 1 83.88 Quite High
Inflammation 1 73.52 Quite High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 9 99.72 Very High Very High Very High
INFLAMMATION 3 86.56 High High
Apoptosis 2 77.08 Quite High
Cardiovascular Disease 1 58.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
JNK and p42/p44 activity was significantly increased in the diabetic heart, while IGF-1R phosphorylation, IRS-2 tyrosine phosphorylation, and Akt activities were reduced.
Negative_regulation (reduced) of Phosphorylation (phosphorylation) of IGF-1R in heart associated with diabetes mellitus
1) Confidence 0.40 Published 2010 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 20555424 Disease Relevance 1.10 Pain Relevance 0.19

General Comments

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