INT16896

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Context Info
Confidence 0.23
First Reported 1991
Last Reported 1993
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (GH1) extracellular region (GH1) plasma membrane (GHSR)
signal transducer activity (GHSR)
Anatomy Link Frequency
plasma 1
GHSR (Homo sapiens)
GH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Clonidine 1 100.00 Very High Very High Very High
Somatostatin 3 99.82 Very High Very High Very High
Potency 1 89.84 High High
Enkephalin 1 65.12 Quite High
Disease Link Frequency Relevance Heat
Hypoglycemia 1 100.00 Very High Very High Very High
Growth Hormone Deficiency 1 71.36 Quite High
Hypopituitarism 1 69.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Because one of the proposed mechanisms of action of GHRP is the inhibition of somatostatin (SS), we tested the effects of propranolol, which inhibits SS, on the GH responses to GHRH and GHRP.
GHRP Regulation (responses) of GH associated with somatostatin
1) Confidence 0.23 Published 1991 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 1856262 Disease Relevance 0 Pain Relevance 0.26
One patient had no response of hGH to hypoglycemia, clonidine and GHRP-1, but the plasma hGH rose to 10 micrograms/l after GHRH.
GHRP-1 Neg (no) Regulation (response) of hGH in plasma associated with hypoglycemia and clonidine
2) Confidence 0.08 Published 1993 Journal Acta Endocrinol. Section Abstract Doc Link 8279223 Disease Relevance 0.24 Pain Relevance 0.10

General Comments

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